April 29, 2008

Obesity surgery seen as potential diabetes cure

Filed under: Diabetes, Obesity Research, Focus28 Experts Blog — The Focus28 Team @ 9:27 pm

Since the Focus28 office lines have been ablaze with phone calls over the last week relating to the recent publicity relating to the potential of obesity surgery being a potential cure for diabetes we felt it was most appropriate to reference an article published earlier this year by the Associated Press relating to the subject.

Obviously this news is monumental and could change the lives of many of those who have been battling both obesity and diabetes for years. Please stay tuned as we continue to report the latest news on the Focus28 expert blog and remember - everyday is a journey and is worth celebrating.

Be well,
The Focus28 team

Obesity surgery seen as potential diabetes cure

CHICAGO, Illinois (AP) — A small new study gives the strongest evidence yet that obesity surgery can cure diabetes.

Obesity is a major risk factor for diabetes; rates for both are climbing.

 Patients who had surgery to reduce the size of their stomachs were five times more likely to see their diabetes disappear over the next two years than were patients who had standard diabetes care, according to Australian researchers.

Most of the surgery patients were able to stop taking diabetes drugs and achieve normal blood tests.

“It’s the best therapy for diabetes that we have today, and it’s very low risk,” said Dr. John Dixon of Monash University Medical School in Melbourne, Australia, lead author of the study, which involved 55 patients.

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April 12, 2008

Omega 3 Fatty Acids

Filed under: Obesity Research — The Focus28 Team @ 11:58 am

The omega 3 fatty acids are a family of essential fatty acids that are necessary for life and health (for review see references 1, 2).  The omega 3 family includes: 1) ALA (alpha-linolenic acid) found in flax, canola oil, soy, walnuts and other nuts, and 2) DHA (docosahexanoic acid) and EPA (eicosapentanoic acid) found primarily in fatty fish (fish oil) and breast milk. All three fatty acids have important health benefits but DHA and EPA are believed to be the most biologically active.
 
Recent studies suggest that the omega 3s, particularly DHA and EPA, have anti-obesity actions3-14. In animals, weight gain and fat accumulation caused by high fat diets are significantly reduced with DHA and EPA7-8, and, in humans, an inverse relationship exists between body size and the omega 3 fatty acids9. The omega 3s may protect against obesity by reducing the body’s capacity to store fat, by increasing fat utilization, and by reducing appetite 3-14.
 
The omega 3 fatty reduce blood lipid levels3-6 (triglyceride and fatty acids) so that less fat is available in the circulating blood to be taken up by and stored in adipose tissue. In addition to lowering lipids in the blood, omega 3s also reduce insulin levels4,5. Insulin increases fat uptake and prevents its breakdown. A decrease in insulin would, therefore, reduce the capacity for adipose tissue to accumulate fat.

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April 7, 2008

Can Tea have Anti-obesity Actions?

Filed under: Nutrition, Obesity Research — The Focus28 Team @ 8:42 am

Obesity is a progressive disease, in part, because weight gain increases the body’s capacity for fat accumulation and reduces its ability to utilize fat. A diet high in fat, sugar and processed grains, further exacerbate these conditions. Regular aerobic exercise, as well as daily consumption of fiber (fruits, vegetables, legumes, whole grains, nuts), dairy or calcium-rich foods, and sufficient amounts of omega 3 fatty acids in appropriate proportion to omega 6, may help to counteract these obesity-promoting changes in fat metabolism.
 
In addition to anti-obesity foods, certain teas, such as green tea, oolong, and black tea, may be effective in correcting those defects in fat handling that cause obesity progression or weight regain. Caffeine is one of the ingredients in teas that is believed to have anti-obesity actions1-3.   Caffeine stimulates the sympathetic nervous system and enhances its actions, causing fat breakdown in adipose tissue and increasing fat oxidation and total energy expenditure (calories burned).

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April 6, 2008

Meal Frequency and Weight Loss Success

Filed under: Nutrition, Obesity Research, Focus28 Experts Blog — The Focus28 Team @ 1:53 pm

How many meals do you eat in a day? 1 large meal? 2 large meals? 5 or more small meals?   Studies have found an inverse relationship between the number of meals a person eats in a day and the prevalence of obesity 1-4. People who eat a number of small meals throughout the day, i.e. those who are ‘nibblers’, are less likely to become obese than are ‘gorgers’ who eat far less frequently but consume large amounts of food at the meal.
 
Weight maintenance after a diet also seems to be affected by the number of meals a person eats. The National Weight Control Registry (NWCR) consists of individuals who have lost at least 60 pounds and have been able to keep their weight off for 6 years or longer.   NWCR members are being studied to determine what weight control behaviors they have that help them to maintain their weight loss5.   An increase in meal frequency is one of these weight control behaviors. NWCR members that are most successful in maintaining their weight loss consume 5 or more small meals throughout the day (including breakfast) instead of 3 or fewer large meals.   

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April 1, 2008

The Anti-obesity Actions of Calcium and Dairy

Filed under: Nutrition, Obesity Research, Focus28 Experts Blog — The Focus28 Team @ 10:18 pm

Do you take your calcium supplements daily?   Do you eat your yogurt, cheese or drink your milk regularly? Calcium deficiencies may readily occur in individuals not taking daily calcium supplements following bariatric surgery. Studies have reported signs of calcium deficits for periods of one to two years1-2 following the adjustable gastric band and for a number of years after Roux-en-Y gastric bypass, the duodenal switch, or the biliopancreatic diversion3-5.
 
An intake of appropriate amounts of calcium is important following surgery to help reduce bone loss, prevent teeth from becoming brittle, and lower the risk for heart disease, hypertension and colon cancer. Calcium is also necessary for muscle contractility, including that of the heart, nerve conductance, and the actions of numerous hormones and enzymes. In addition, dietary calcium is believed to play a role in the regulation of body size. Low dietary calcium intake increases the risk for weight gain; and high dietary calcium, particularly from dairy foods, cause favorable changes in body composition (less body fat and more lean tissue) and fat distribution (preferential reduction of abdominal fat) 6-8

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March 18, 2008

Sleep Loss and Obesity

Filed under: Obesity Research, Focus28 Experts Blog — The Focus28 Team @ 8:42 pm

A chronic state of sleep loss is believed to be one of a multitude of factors responsible for the alarming rise in obesity prevalence that has been occurring over the last several decades. According to the Center for Disease Control, this rise in obesity prevalence has been mirrored by a decline in sleep duration(see reference 1 for review).    A generation ago, Americans slept for 8 to 9 hours per night2. By the mid-1990’s, however, sleep duration had declined to 7 hours or less3. More recent data (2004) show that a substantial number of Americans are now sleeping for 6 hours or less each day4.

Epidemiological studies from the U.S. and other countries find negative associations between sleep duration and overweight1,5-14. According to these studies, the lowest risk for obesity in adults occurs with a sleep duration of 7 to 8 hours. Periods of sleep that are less than 7 hours, however, are inversely related to body size. In other words, the shorter the duration of sleep, the higher would be a person’s body mass index and their accumulation of body fat. One study reported a 2.8% increase in body fat for each hour of sleep that is less than 7 hours per night14.  Two additional long-term studies15-16 found that individuals who obtain the least amount of sleep are those who gain the most weight over time.

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March 17, 2008

Childhood & Adolescent Obesity

Filed under: Nutrition, Obesity Research — The Focus28 Team @ 9:15 am

Obesity in children and adolescents is defined using a measure of body Mass index (BMI), however, unlike for adults, there is no critical BMI that describes obesity. Instead it is plotted on a growth chart as a percentile. Overweight and obesity for children (ages 6 to 11) and adolescents (age 12 to 19) are defined respectively as being at or above the 85th and 95th percentile of body mass index. There are many contributing factors in the development of childhood and adolescent obesity – some are modifiable and others are not.
 

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March 6, 2008

Obesity: The Mother of Disease

Filed under: Obesity Research, Focus28 Experts Blog — The Focus28 Team @ 12:00 pm

The world is facing its first-ever obesity epidemic and some experts believe that this epidemic may prove to be far more deadly than the worst of famines. Why? Because there is a known cause and cure for hunger, whereas, obesity has multiple causes and no known long-term cure.
 
According to the results of a nearly decade-old epidemiological study, more than 65% of Americans are overweight.   Data from another large nationwide study shows that with each passing year the numbers and severity of obesity are increasing at an alarming rate.   Such findings would not be so serious if obesity were only a cosmetic issue. Obesity, however, is a disease that both costs and kills.

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